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Next Generation PRF + Biomaterials

An Advanced Course on Selecting Appropriate Biomaterials for

Bone and Periodontal Regeneration using PRF

with Dr. Richard Miron and Quintessence International

Advanced Course in Biomaterials

New Date

December 8-10, 2023, Fort Lauderdale, FL

Click on the link above for course location information.

Location: Nova Southeastern University

3200 South University drive, Fort Lauderdale, FL 33328


Partnering Hotel: 

Renaissance Fort Lauderdale-Plantation Hotel

1230 S Pine Island Rd, Plantation, FL 33324

“This is our most Advanced Program in PRF + Biomaterials and was designed to provide clinicians with thorough knowledge on when to utilize which biomaterials in clinical practice.”

Its content is derived from Dr. Richard Miron's best-selling textbook!!

Course Description


New and innovative biomaterials are being discovered or created in laboratories at an unprecedented rate, but many of them remain entirely foreign to practicing clinicians. This course addresses this gap in knowledge by summarizing some of the groundbreaking research performed to date on this topic and providing case examples of these biomaterials at work. The course begins with a review of the biological background and applications of bone grafting materials utilized in dentistry. The principles of guided tissue and bone regeneration are covered in detail, including many recent advancements in barrier membrane technologies as well as use of platelet-rich fibrin and various growth factors, and many next-generation materials that will optimize future bone and periodontal regeneration are presented. The final section of the course is designed to help clinicians select appropriate biomaterials for each specific regenerative protocol. Much like one implant size and shape cannot be utilized for every indication in implant dentistry, one bone grafting material, barrier membrane, or growth factor cannot maximize regenerative outcomes in all clinical situations. This course teaches clinicians how to utilize biomaterials in an appropriate, predictable, and evidence-based manner.

Unfortunately the majority of biomaterial education provided to clinicians in private practice is conducted by sales reps. Owing to their limited biomaterial portfolio and knowledge on the topic, often incorrect decisions are made by the treating clinician. This course provides the evidence-base decision making process for those that wish to maximize either bone or periodontal regeneration.

Autogenous bone.png

Course Outline

Day 1 Objectives:

Understand the different available options for bone grafts and their uses. Understand when to utilize each class of bone grafting material appropriately


08:30-09:30 Biomaterials and their effect on immune health and tissue integration. How to optimize regenerative strategies by minimizing immune responses. How to supplement patients with antioxidants, vitamin D and other vitamins to minimize graft/implant failure.


09:30-10:15 Classification of bone grafting materials. Current uses and percentages of bone grafting materials in North America. Why do we use autografts versus allografts, versus xenografts versus synthetic materials.


10:15-10:45 Coffee break


10:45-11:15 Autogenous bone, the gold standard of bone regeneration. Importance of harvesting techniques. When block graft, when particles. The bone scraper and its simplistic use in implantology. Are autografts still the gold standard? Introduction to the concept of bone conditioned media (BCM).


11:15-12:00 Allografts, the standard replacement material. Differences between freeze-dried bone allograft (FDBA) and demineralized freeze-dried bone allografts (DFDBA). Clinical uses of FDBA versus DFDBA. Understanding that processing technique of bone allografts is extremely important for bone-inducing potential and that not all allografts are the same.


12:00-01:00 Lunch break


01:00-01:45 Xenografts – why are they so heavily utilized in North America? What are their advantages and disadvantages. Clinical cases presented with their relative indications.


01:45-02:30 Synthetic materials – uses and limitations. Osopia, the next generation and first osteoinductive synthetic bone graft.


02:30-03:00 Break


03:00-03:45 Dentin Grinder – uses and limitations. Does every tooth deserve a second chance?


03:45-04:00 Live demo of the dentin grinder


04:00-04:45 Tetranite, a novel bone adhesive that adheres dental implants directly to bone giving optimal primary stability of dental implants. Discussion on the future of 3D printed bone grafts


Day 2 Morning Objectives:

Understand the objective use of barrier membranes and platelet rich fibrin.


08:30-09:15 Barrier membranes, when non-cross-linked, when cross-linked? When non-resorbable? When titanium? Expert discussion with case presentations from leaders in the field.


09:15-11:00 Advanced concepts in platelet rich fibrin (PRF). What you don’t know about PRF that you probably should know. Updates from the Miron Research Lab.


11:00-12:00 Blood draws with advanced concepts. Novel centrifugation speeds and the future of PRF tubes.


12:00-01:00 Lunch


Day 2 Afternoon objectives:

Understand why growth factors are the future of bone and periodontal regeneration. Understand each class of growth factors and their uses.


01:00-01:30 Growth factors for bone regeneration. BMP2 and BMP9. Uses and applications. When to replace autogenous bone harvesting?


01:30-02:15 Enamel matrix derivative (Emdogain) and its effect on periodontal regeneration. Osteogain, a next generation growth factor for periodontal regeneration.


02:15-02:30 Combination approaches to periodontal regeneration. Clinical uses of rhPDGF (Gem21) and rhFGF2


02:30-03:00 Break


03:00-03:30 Use of Exosomes for soft tissue regeneration. Is it a next generation biomaterial? Clinical evidence from European studies.


03:30-03:45 Ion incorporation into bone grafts for bone and periodontal regeneration. Can we 'dope' bone grafts? Use of gene therapy for growth factor delivery – is there a future?


03:45-05:00 Clinical recommendations and guidelines for selecting appropriate biomaterials for bone and periodontal regeneration in an appropriate, predictable, and evidence-based manner. Evidence discussing what biomaterials to use for extraction sockets, sinus augmentations, GBR procedures, around implants, periodontal regeneration, and recession coverage.

Day 3 Hands-on Training & Live Demonstrations

The course usually concludes at 2:00pm.

Advanced Course in Biomaterials

“This Advanced Program in Next Generation Biomaterials was designed to provide clinicians with thorough knowledge on when to utilize which biomaterials in clinical practice.”

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