Unlocking the Power of Your Platelets: APCs in Facial Rejuvenation

Advanced PRF Education
Sep 11
2 min read

Source: https://drive.google.com/file/d/1Lrh9ZsdjMAjk-CjVSEm8TW3JGOLzUF1X/view

Autologous platelet concentrates (APCs)—also known as PRP (platelet-rich plasma), PRGF (plasma rich in growth factors), or PRF (platelet-rich fibrin)—are making waves in esthetic medicine for their regenerative potential harnessed directly from your own blood. A newly published narrative review by Davies and Miron dives into how APCs are transforming facial esthetics, summarizing nearly 96 clinical studies up to October 2023 .

Key Applications in Facial and Dermatologic Treatment Include:

Scar revision
Skin rejuvenation
Melasma and hyperpigmentation management
Vitiligo support
Stretch mark improvement
Periorbital and peri-oral rejuvenation
Hair regeneration
Volume restoration using APC-compatible gels

Most studies report positive outcomes with PRP, and several indicate that PRF may offer superior results . Still, researchers highlight that many trials suffer from small sample sizes and inconsistent assessment methods. Future studies should adopt better-designed randomized controlled trials with standardized protocols and objective outcome measures .

Insights from Lab to Clinic: What Happens at the Cellular Level?

The article showcases foundational laboratory research on liquid-PRF vs. PRP vs. control using human skin fibroblasts:

Liquid-PRF dramatically boosts cell migration, reaching almost 350% of control levels, compared to PRP’s 200% .
Gene expression for key regenerative markers—PDGF, TGF-β, collagen (COL1), and fibronectin (FN1)—was consistently higher with liquid-PRF at both 3 and 7 days compared to controls and PRP .

These findings underline the cellular advantages of liquid-PRF, including enhanced migration and upregulated genes essential for tissue regeneration—scientific proof that feeds directly into advanced clinical practice.

How This Article Aligns with the Advanced PRF in Facial Esthetics Course

Advanced PRF Education’s 3-Day Facial Esthetics Course teaches exactly these principles in action—covering the biology, techniques, and hands-on skills to elevate your clinic's capabilities PRF EDU.

Day 1 focuses on biologic foundations: why platelet concentrates accelerate wound healing, updated centrifugation protocols, and the formulation of liquid vs. membrane PRF—including the advanced Bio-Cool/Bio-Heat methods that extend PRF longevity up to 4–6 months.

Days 2 and 3 dive into hands-on mastery:

Live demonstrations on micro-needling with PRF, PRF injections, Bio-Filler creation, and hair regeneration techniques.
This directly translates the science from the article—such as leveraging liquid-PRF for enhanced cell behavior—into practical, clinic-ready skills.

Additionally, the course is led by experts including Dr. Richard Miron and Dr. Catherine Davies, the very authors behind the article you’ve just read—creating continuity between research and clinical practice.

Ready to Learn & Apply the Latest in PRF Esthetics?

If you're eager to refine your skills, understand the science, and deliver cutting-edge treatments—from microneedling to biological fillers—the 3-Day Advanced PRF in Facial Esthetics Course is your gateway.

Why Attend:

Ground your practice in evidence-based biology
Master liquid-PRF and Bio-Filler techniques, backed by measurable gene and cell effects
Train directly with Davies, Miron, and leading experts in dental and medical aesthetics